The insertion of a neomycin selection cassette disrupted the exon encoding the subdomain I of the kinase domain. The absence of protein in mice homozygous for the allele was verified by Western blot analysis. (J:29796, J:97055)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count