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A human CTNNB1 gene deleted for 89 N-terminal amino acids was used for the transgene. Nucleotides -596 to +21 from Fabpl were used to drive expression of the transgene in intestinal epithelium. RT-PCR analysis confirmed the expression of the transgene. Western blot of total jejunal proteins and immunohistochemistry of jejunal sections confirmed transgene protein product in transgenic animals. (J:47861)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
