Tg(Fabpl-CTNNB1)1Jig

A human CTNNB1 gene deleted for 89 N-terminal amino acids was used for the transgene. Nucleotides -596 to +21 from Fabpl were used to drive expression of the transgene in intestinal epithelium. RT-PCR analysis confirmed the expression of the transgene. Western blot of total jejunal proteins and immunohistochemistry of jejunal sections confirmed transgene protein product in transgenic animals. (J:47861)