Chimeric animals carrying the targeted mutation Ppyr1tm1Hhz were crossed to a cre-expressing line to facilitate excision of the neo cassette and the entire coding sequence of Ppyr1. The deletion was confirmed in the offspring by Southern blot analysis. (J:76479)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count