Single loxP sites were left flanking exons 2 and 3 after homologous recombination of a targeting vector and the subsequent removal of a floxed neo cassette. Deletion of the floxed region will result in a frameshift mutation at exon 4. (J:76493)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count