The transgenic construct was generated by inserting sequence encoding NLS-cre recombinase into a BAC encompassing the 5' portion of the murine Otog gene. Otog is endogenously expressed in the inner ear. Cre was flanked upstream by the Otog promoter and UTR of exon 1 and downstream by the coding region of exon 1 and all of exon 2. (J:77823)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count