The targeted mutation is a derivative of Vdrtm1Gcm. Exon 2 was deleted by crossing animals carrying Vdrtm1Gcm to a cre-expressing line. Absence of gene expression in homozygous mutant animals was demonstrated by RT-PCR analysis of duodenum, kidney, and bone tissue. (J:72578)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count