This allele was generated by transient transfection of ES cells harboring Ktntm1Kpf with a cre expression plasmid. The excision of neomycin was mediated by the expression of cre, leaving exons 3 through 5 flanked by loxP sites. Encoded protein was detected in homozygous mutant mice via Western blot analysis. (J:77650)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count