The majority of exon 3 was replaced with 2 tandem copies of the FLAG epitope tag and a loxP-flanked MC1-neo cassette was inserted 2.5 kb upstream of the promoter via homologous recombination. (J:77714)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count