Exon 2 was disrupted by the insertion of a neomycin selection cassette 219 base pairs downstream of the translational start codon. Northern blot analyses showed the exclusive presence of truncated transcript containing the neo transgene in homozgous mutant mice. (J:77226)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count