Log In|Sign Up
EN
Most of the coding region of the gene was replaced with a PGK-neo cassette facing the opposite orientation via homologous recombination leaving the first 22 codons intact. Northern blot analysis using a probe to the coding region showed decreased expression in the brain and almost no expression in testes of homozygous mutant animals. The low level of transcript detected is presumed to be Siah1b, which also hybridizes to the probe. (J:75489)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
