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This allele is a derivative of Egr2tm3Pch in which exon 2 and flanking sequences were deleted by Cre mediated recombination. Mice carrying the Egr2tm3Pch allele were mated to Tg(Pgk1-cre)1Lni mice and offspring were screened for the heritable deletion. Immunohistochemistry experiments on homozygous embryos demonstrated that no detectable protein was encoded by this allele. (J:75128)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
