Exons 2 through 4 were replaced by a cassette containing a nls-lacZ gene followed by a floxed neomycin gene. Neither transcript nor protein was detected in skin of homozygous mutant mice by Northern and Western blot analyses. (J:75715)
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Exons 2 through 4 were replaced by a cassette containing a nls-lacZ gene followed by a floxed neomycin gene. Neither transcript nor protein was detected in skin of homozygous mutant mice by Northern and Western blot analyses. (J:75715)