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This allele was generated by breeding mice heterozygous for Evx1tm1Gld and transgenic mice expressing cre with a protamine promoter. Expression of cre excised the portion of the homeodomain encoded by exon 3 and a neo gene, leaving IRES-tau-myc in the 3' untranslated region. Analysis of transverse sections of heterozygous mutant embyros showed that the expression of tau-myc resembled that of the endogenous gene. (J:70192)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
