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A transgene consisting of a chicken beta actin promoter, followed by a GFP (green fluorescence protein) expression cassette flanked by two lox sites and preceding a human K-RasV12 cDNA combined with an ALPP (PLAP; human placenta-like alkaline phosphatase) expression construct. Expression of oncogenic K-RasV12 is dependent on Cre-mediated deletion of the GFP fragment. (J:72206)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
