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The gene was disrupted by replacing part of exon 1 with a lacZ-PGK-neo cassette via homologous recombination resulting in fusion of the lacZ gene 16 bp upstream of the ATG start codon. Gene expression was absent in homozygous mutant animals as shown by RT-PCR analysis using different sets of primers to the gene. (J:76005)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
