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A portion of the gene from intron 5 to exon 9 was replaced with a PGK-neo cassette via homologous recombination resulting in the deletion of the coenzyme binding site encoded by exon 8. Northern blot analysis of kidneys from homozygous mutant animals verified the absence of gene expression. (J:70702)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
