The majority of exons 6 and 7 was replaced with a neomycin selection cassette. The replaced region encoded all zinc fingers of the encoded protein. Western blot analysis of homozygous mutant embryonic tissue showed an absence of protein. (J:63121)
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The majority of exons 6 and 7 was replaced with a neomycin selection cassette. The replaced region encoded all zinc fingers of the encoded protein. Western blot analysis of homozygous mutant embryonic tissue showed an absence of protein. (J:63121)