A neomycin selection cassette replaced genomic sequence encoding amino acids 53 through 332 (the carboxy terminus) of the encoded protein. The deletion includes all the coding sequence for the mature, processed form of the protein. Northern blot analysis revealed that no transcripts expressed from this gene were present in RNA derived from homozygous mice. (J:77247)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S1/Sv-Oca2+ Tyr+ Kitl+
Targeted
Insertion, Intragenic deletion
--
1
--
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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