A hypomorphic allele was generated by the insertion of the operater sequence (lacO) from the lac operon in intron 3 via recombinatory techniques. Quantitation of Northern blot analysis results showed a 40% reduction in transcript levels versus wild-type. (J:75230)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count