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Exon 1 was disrupted by the insertion of a cassette containing an IRES-tau-lacZ gene, a floxed neomycin gene, and a SV40 polyadenylation signal. The absence of encoded protein in the of homozygous mutant embryos was determined using antisera. Staining of heterozygotes showed the expression pattern of beta-galactosidase to be similar to that of the endogenous gene. (J:57340)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
