A HPRT minigene, flanked by loxP sites, was inserted into intron 1. An additional loxP site was inserted in the 3' untranslated region. Mice heterozygous for this allele were used to generate Cyp1a1tm1.1Dwn. (J:59398)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count