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The gene was disrupted by replacement of most of exon 1 with a neomycin resistance cassette via homologous recombination resulting in the deletion of sequences encoding the kinesin motor domain. Lack of gene expression in homozygous mutant E9.5 embryos was confirmed by Western blot analysis. (J:51419)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
