The gene was disrupted by insertion of a PGK-neo cassette into exon 2 via homologous recombination. Western blot of whole eye membrane protein confirmed the absence of protein expression in homozygous mutant mice. (J:77333)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count