The entire coding region was replaced by a construct containing a beta-geo fusion gene, lacking a promoter. Recombination of the construct left the 5' flanking region intact, enabling the expression of the beta-geo transgene to be under the control of the endogenous promoter and regulatory sequences. (J:62026)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S/SvEv-Gpi1c
Targeted
Insertion, Intragenic deletion
--
1
6
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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