The gene was disrupted by insertion of a neomycin resistance cassette into exon 2 via homologous recombination. Western blot analysis verified the absence of protein expression in homozygous mutant embryos. (J:57825)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count