The gene was disrupted by insertion of a lacZ-neo cassette into exon 7 encoding the DNA-binding domain via homologous recombination. Western blot analysis of liver nuclear protein from homozygous mutant animals verified the absence of gene expression. (J:42599, J:75776)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count