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A promoterless neomycin resistance gene was inserted in frame into exon 10, and all of intron 10 and part of exon 11 were deleted. The deleted sequences encode part of the DNA binding domain and the leucine zipper domain. RT-PCR analysis on total brain RNA demonstrated that no transcripts containing the 3' end were detectable; however, a fusion transcript containing the lacZ sequences is detected. (J:47431)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
