This hypomorphic allele is a derivative of Bmp4tm3Blh. LoxP sites were inserted flanking exons 3 and 4, and a promoterless lacZ gene was inserted 3' to the loxP insertions. An frt-flanked neomycin selection cassette that was inserted downstream of the lacZ gene was removed by Flpe mediated recombination in the final allele. (J:75136)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count