LoxP sites were inserted flanking exons 3 and 4, and a promoterless lacZ gene was inserted 3' to the loxP insertions. An frt-flanked neomycin selection cassette was also inserted downstream of of the lacZ gene. This allele is reported to behave as a hypomorph. (J:75136)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
Insertion
--
1
5
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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