A construct containing a beta-geo fusion marker as well as a splice-acceptor site and a picornaviral internal ribosome-entry site (IRES) was inserted upstream of exon 8 and 9. The construct was designed to prevent the translation of the functionally essential centromere targeting region. Southern blot analysis confirmed the targeting event. (J:45656)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Targeted
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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