A neomycin selection cassette replaced 200 nucleotides in exon 3 of Cd1d1, while leaving the adjacent Cd1d2 locus intact. Thymocytes derived from homozygous mutant mice were shown to lack protein surface expression. This finding was confirmed by the inability of a specific hybridoma to recognize thymocytes from homozygous mutant mice. (J:39748)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
Intragenic deletion
--
1
--
134

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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