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A neomycin cassette replaced the region encoding a portion of the tyrosine kinase-binding and RING finger domains, corresponding to amino acids 300 through 340 of the encoded protein. Western blot analysis showed an absence of protein expression in lymph nodes and splenocytes from homozygous mice. (J:76896)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
