The gene was disrupted by replacement of exon 1 with a neomycin resistance cassette via homologous recombination. Absence of gene expression in homozygous mutant mice was confirmed via RT-PCR analysis of spleen cell RNA. (J:76414)
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The gene was disrupted by replacement of exon 1 with a neomycin resistance cassette via homologous recombination. Absence of gene expression in homozygous mutant mice was confirmed via RT-PCR analysis of spleen cell RNA. (J:76414)