A neomycin selection cassette was used to replace a 2 kb region containing exon 1 and its flanking sequence. An absence of mRNA and protein were observed in T cells isolated from the lymph nodes of homozygous mutant mice by Northern blot and Western blot analysis, respectively. (J:73833, J:96620)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S6/SvEvTac
Targeted
Insertion, Intragenic deletion
--
1
2
291

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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