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A neomycin selection cassette replaced a region encoding the cysteine finger of the CR1 domain, the entire CR2 domain, and the ATP-binding site of the CR3 domain. Western blot analysis of embryonic fibroblasts derived from hemizygous mice indicated an absence of protein encoded by the targeted locis and showed normal levels of protein produced by an adjacent locus. (J:33951)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
