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Exon 2 was disrupted by insertion of a PGK-neo cassette via homologous recombination resulting in the introduction of multiple stop codons and translation termination before the first transmembrane domain. Absence of gene expression was verified by Western blot analysis of brain membrane protein from homozygous mutant animals. (J:63515)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
