A PKC-neo cassette was used to replace exon 5, which contains the translation initiation site and the entire coding sequence. Northern analysis of RNA isolated from the liver, brain, and kidney of homozygous mutant mice revealed an absence of message. (J:44975)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count