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0.7 kb of the gene including exon 1 was replaced with a neomycin resistance cassette by homologous recombination. Northern and Western blots of brain and nervous tissue from homozygous mutant animals did not detect gene expression, nor were any truncated mRNA species or protein fragments detected. (J:44421)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
