Log In|Sign Up
EN
A tyrosine to phenylalanine substitution at amino acid 90 (p.Y90F) was introduced via homologous recombination. The resulting protein product is enzymatically inactive yet retains structural integrity and DNA binding ability. The Y90F point mutation was verified via RT-PCR and restriction digest analysis of RNA transcripts from mutant animals. (J:75891)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
