A self-excising cre-neomycin resistance cassette replaced 213 bp of coding sequence at the 5' end of the gene, and placed the open reading frame of EGFP, followed by the late SV40 polyadenylation signal, inframe with upstream sequences. The B cell lineage expression pattern from this allele visualized using EGFP matches that of wild-type gene expression previously described using a mouse-specific monoclonal antibody. (J:73935)
Basic Information
Insertion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count