Exon 2 of this gene was disrupted by the insertion of a neo cassette via homologous recombination. Northern blot analysis detected mutant transcript from the stomachs of homozygous mutant animals. Western blot of gastric cytosol and immunohistochemistry of stomach from homozygous mutant animals did not detect protein product. (J:35923)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S2/SvPas
Targeted
Insertion
--
1
--
22

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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