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54 nucleotides of exon 5 and 187 nucleotides of intron 5 were replaced with a neo-derived cassette via homologous recombination resulting in the deletion of the ATP-binding motif of domain II responsible for DNA repair and recombination. Homozygous mutant embryos could only be detected before the 4- to 8- cell stage by PCR analysis. (J:33832)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
