An IRES-lacZ reporter gene followed by a loxP-flanked neomycin resistance cassette was inserted into exon 5, which encodes part of the T box domain resulting in a functionally null allele. (J:67409)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count