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This allele is a derivative of Otx2tm4.1Sia in which the loxP-flanked sequences were removed by crossing mice carrying the Otx2tm4.1Sia allele to mice expressing Cre recombinase in the germline [TgN(ACTB-Cre)2Mrt]. The final allele carries a single loxP site in place of the promoter and first exon of the gene, and a single frt site in place of the frt-flanked neomycin cassette. (J:74631)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
