Egfr^Wa5

Originally named Waved 5, this phenotypic mutant was deemed allelic to Egfr when it failed to complement Egfrtm1Mag. The entire coding region of Egfr was subsequently sequenced. A single point mutation was found causing a GAT to GGT missense mutation in exon 21. This results in an aspartic acid to glycine change at amino acid residue 833 altering a DFG motif critical to the tyrosine kinase function of this gene. (J:75964, J:92308)