A gene trap vector inserted into intron 1, causing the expression of an abnormal transcript that is interrupted after codon 26. Western blot analysis on extracts of embryos or embryonic fibroblasts derived from homozygous embryos confirmed that no detectable protein was expressed from this allele. (J:54197)
Basic Information
STOCK 129/Sv and C57BL/6J and SJL
Insertion of gene trap vector
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count