A gene trap vector inserted into intron 1, causing the expression of an abnormal transcript that is interrupted after codon 26. Western blot analysis on extracts of embryos or embryonic fibroblasts derived from homozygous embryos confirmed that no detectable protein was expressed from this allele. (J:54197)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
STOCK 129/Sv and C57BL/6J and SJL
Gene trapped
Insertion of gene trap vector
--
1
13
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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