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Insertion of a neomycin resistance cassette into the E12-specific exon disrupted the gene. RT-PCR studies of fetal liver and of lung from 5 week old mice detected trace amounts of E47-specific transcript in homozygous mutant mice. The authors predict that both gene products, E12 and E47, are inactivated in this allele. (J:67011)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
