Grin1^tm2.1Phs

This allele is a derivative of Grin1tm2Phs. Point mutations were introduced that altered codon 598 in exon 15 from one encoding asparagine to one encoding arginine. A loxP-flanked neomycin selection cassette in intron 18 was removed by transient Cre recombinase expression in ES cells prior to the production of chimeric mice. (J:75497)