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This allele is a derivative of Grin1tm1Phs. Point mutations were introduced that altered codon 598 in exon 15 from one encoding asparagine to one encoding glutamine. A loxP-flanked neomycin selection cassette in intron 18 was removed by transient Cre recombinase expression in ES cells prior to the production of chimeric mice. (J:75497)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
