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This transgene directs the expression of Cre recombinase under the control of a phosphoglycerate kinase promoter, with integration site effects. Expression of this transgene is under dominant maternal control, probably due to cis acting effects at the integration site. SNP typing indicates that it is likely the transgene integrated into a Chr 4 locus of BALB/c origin. Activity is thought to commence at the diploid phase of oogenesis, and directs complete recombination in all tissues of progeny derived from mothers carrying the transgene. (J:69332)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
